Article
P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia.
Biological psychiatry - 1 Apr 2004
Myles-Worsley Marina, Ord Lisa, Blailes Francisca, Ngiralmau Hilda, Freedman Robert
Abstract excerpt
BACKGROUND: Gating or inhibition of the P50 auditory evoked potential is a heritable neurobiological trait that has shown strong potential to serve as an endophenotype for schizophrenia. P50 sensory gating deficits have been found repeatedly in schizophrenic patients and in their unaffected first-degree relatives. P50 sensory gating has not yet been studied in high-risk (HR) offspring nor in prodromal...
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