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Further evidence for shared genetic effects between psychotic bipolar disorder and P50 suppression: A combined twin and family study

11 Jan 2008

Abstract excerpt

P50 suppression deficit has been reported in patients with psychotic bipolar disorder. In our previous report on twin pairs concordant and discordant for bipolar disorder, we found significant genetic overlap between bipolar disorder and P50 sensory gating. However, the sample size in that study was relatively small. A separate study, the Maudsley Bipolar Family Study, reported diminished P50 gating in unaffected...

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PMID: 18189279
DOI: 10.1002/ajmg.b.30653

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