Article
Association of PPARG2 Pro12Ala variant with larger body mass index in Mestizo and Amerindian populations of Mexico.
Human biology - 1 Feb 2007
Canizales-Quinteros S, Aguilar-Salinas C A, Ortiz-López M G, Rodríguez-Cruz M, Villarreal-Molina M T, Coral-Vázquez R, Huertas-Vázquez A, Hernández-Caballero A, López-Alarcón M, Brito-Zurita O R, Domínguez-Banda A, Martinez-Sánchez L R, Canto-de Cetina T, Vilchis-Dorantes G, Rosas-Vargas H, Granados-Silvestre M A, Medeiros-Domingo A, Menjivar M, Tusié-Luna M T
Abstract excerpt
Previous studies have sought to associate the Pro12Ala variant of the peroxisome proliferator-activated receptor gamma2 (PPARG2) gene with type 2 diabetes, insulin resistance, and obesity, with controversial results. We have determined the Pro12Ala variant frequency in 370 nondiabetic Mexican Mestizo subjects and in five Mexican Amerindian groups and have investigated its possible association with lipid...
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