Article
D-Glucose-recognition and phlorizin-binding sites in human sodium/D-glucose cotransporter 1 (hSGLT1): a tryptophan scanning study.
Biochemistry - 27 Nov 2007
Tyagi Navneet K, Kumar Azad, Goyal Pankaj, Pandey Dharmendra, Siess Wolfgang, Kinne Rolf K H
Abstract excerpt
In order to gain a better understanding of the structure-function relation in hSGLT1, single Trp residues were introduced into a functional hSGLT1 mutant devoid of Trps at positions that previously had been postulated to be involved in sugar recognition/translocation and/or phlorizin binding. The...
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