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Article

Identification of a disulfide bridge linking the fourth and the seventh extracellular loops of the Na+/glucose cotransporter.

The Journal of general physiology - 1 Feb 2006

Gagnon Dominique G, Bissonnette Pierre, Lapointe Jean-Yves

Abstract excerpt

The Na+/glucose cotransporter (SGLT1) is an archetype for the SLC5 family, which is comprised of Na+-coupled transporters for sugars, myo-inositol, choline, and organic anions. Application of the reducing agent dithriothreitol (DTT, 10 mM) to oocytes expressing human SGLT1 affects the protein's presteady-state currents. Integration of these currents at different membrane potentials (Vm) produces a Q-V curve,...

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Identifiers

PMID: 16446504
DOI: 10.1085/jgp.200509439
PMCID: PMC2151483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a disulfide bridge linking the fourth and the seventh extracellular loops of the Na+/glucose cotransporter.PMID 16446504Read ↗

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