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Article

The Role of CXCL12 in Kidney Diseases: A Friend or Foe?

1 Jan 2021

Abstract excerpt

BACKGROUND: Chemokines are a family of proteins mainly mediating the homing and migration of various cells. The CXC chemokine CXCL12 is a member of low-weight-molecular chemokines. In the kidney, CXCL12 is pivotal for renal development and exerts a modulatory effect in kidney diseases under different etiologic settings by binding with CXC chemokine receptor 4 (CXCR4) or CXC chemokine receptor 7 (CXCR7). Besides,...

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Share to Chemokine receptors and signaling
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PMID: 34179113
DOI: 10.1159/000514913

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