Article
Lack of association between matrix metalloproteinase-1 (MMP-1) promoter polymorphism and risk of renal cell carcinoma.
International braz j urol : official journal of the Brazilian Society of Urology - 1 Jan 2000
Piccoli Michelly F, Figueira Marcia, Andreoni Cassio, Marumo Julio T, Schor Nestor, Bellini Maria H
Abstract excerpt
OBJECTIVE: Investigate the possible association of insertion/deletion (2G/G) polymorphism at nucleotide -1607 of the MMP-1 promoter with the development and progression of renal cancer. MATERIALS AND METHODS: In this study, we genotyped 217 individuals, 99 patients with renal cell carcinoma (RCC) and 118 controls without cancer. DNA specimens were extracted from epithelial buccal cells and paraffin-embedded...
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