Article
A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter is associated with conventional renal cell carcinoma.
International journal of cancer - 1 Sept 2003
Hirata Hiroshi, Naito Katsusuke, Yoshihiro Satoru, Matsuyama Hideyasu, Suehiro Yutaka, Hinoda Yuji
Abstract excerpt
Matrix metalloproteinase (MMP)-1 is associated with tumor cell invasion and metastasis, and its promoter polymorphism has been shown to influence the transcriptional level. Our study explored the association between this polymorphism and renal cell carcinoma in a Japanese population. DNA was extracted from peripheral blood and normal tissue of 119 patients with conventional renal cell carcinoma (RCC) and from 210...
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