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Insights into Matrix Metalloproteinase-2 Genotypes, Smoking, Alcohol Drinking, Hypertension and Renal Cell Carcinoma in Taiwan.

Anticancer research - 1 Jul 2026

Chang Shu-Yu, Tsai Hung-Wen, Wang Bo-Ren, Yang Ya-Chen, Chen Jaw-Chyun, Tsai Chia-Wen, Bau DA-Tian, Chang Wen-Shin

Abstract excerpt

BACKGROUND/AIM: Renal cell carcinoma (RCC) accounts for more than 90% of kidney malignancies worldwide. Matrix metalloproteinase-2 (MMP-2) has been reported to be dysregulated in multiple cancers. However, the relationship between MMP-2 genetic polymorphisms and RCC risk has rarely been investigated. This study aimed to evaluate the associations of two promoter polymorphisms, MMP-2 rs243865 and rs2285053, with...

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Identifiers

PMID: 42373263
DOI: 10.21873/anticanres.18240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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