Article
The Association of Matrix Metalloproteinase-1 Promoter Polymorphisms with Breast Cancer.
In vivo (Athens, Greece) - 1 Jan 2000
Hsiao Chieh-Lun, Liu Liang-Chih, Shih Tzu-Ching, Lai Yi-Liang, Hsu Shih-Wei, Wang Hwei-Chung, Pan Su-Yi, Shen Te-Chun, Tsai Chia-Wen, Chang Wen-Shin, Su Chen-Hsien, Way Tzong-DER, Chung Jing-Gung, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: The family of matrix metalloproteinases (MMPs) are responsible for the homeostasis of extracellular matrix components and their genetic polymorphisms may be associated with cancer susceptibility. The serum levels of MMP-1 have been reported to be lower in breast cancer patients than healthy subjects. In the current study, we aimed at investigating the contribution of a polymorphism in the promoter...
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