Article
The Contribution of MMP-7 Promoter Polymorphisms in Renal Cell Carcinoma.
In vivo (Athens, Greece) - 1 Jan 2000
Liao Cheng-Hsi, Chang Wen-Shin, Hu Pei-Shin, Wu Hsi-Chin, Hsu Shih-Wei, Liu Yen-Fang, Liu Shih-Ping, Hung Huey-Shan, Bau DA-Tian, Tsai Chia-Wen
Abstract excerpt
BACKGROUND/AIM: Mounting evidence has suggested that polymorphisms in the promoters of matrix metalloproteinase (MMP) genes are associated with the risk of many types of cancer, but no study has ever explored these polymorphisms as biomarkers for renal cell cancer (RCC). Recently, it was suggested that serum MMP-7 levels have both diagnostic and prognostic potential for RCC. In this study, we focused on the...
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