Article
Down-regulation of MTUS1 in human colon tumors.
Oncology reports - 1 Jan 2010
Zuern Christina, Heimrich Jutta, Kaufmann Roland, Richter Konrad K, Settmacher Utz, Wanner Christoph, Galle Jan, Seibold Stefan
Abstract excerpt
Loss of proliferative control and failure to undergo cellular differentiation are key events during carcinogenesis. We recently identified a new potential tumor suppressor gene named MTUS1 (mitochondrial tumor suppressor 1), down-regulated in undifferentiated tumor cell lines, inhibiting tumor cell proliferation after recombinant over-expression. The aim of this study was to investigate whether MTUS1 is also...
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