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Article

Pho85p-Pho80p phosphorylation of yeast Pah1p phosphatidate phosphatase regulates its activity, location, abundance, and function in lipid metabolism.

The Journal of biological chemistry - 30 Mar 2012

Choi Hyeon-Son, Su Wen-Min, Han Gil-Soo, Plote Devin, Xu Zhi, Carman George M

Abstract excerpt

The yeast Pah1p phosphatidate phosphatase, which catalyzes the penultimate step in the synthesis of triacylglycerol and plays a role in the transcriptional regulation of phospholipid synthesis genes, is a cytosolic enzyme that associates with the nuclear/endoplasmic reticulum membrane to catalyze the dephosphorylation of phosphatidate to yield diacylglycerol. Pah1p is phosphorylated on seven (Ser-110, Ser-114,...

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Cyclin-Dependent Kinases
Cyclins
Lipid Metabolism
Liposomes
Phosphatidate Phosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Transport

Saccharomyces cerevisiae Proteins

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PMID: 22334681
DOI: 10.1074/jbc.M112.346023
PMCID: PMC3322823

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Pho85p-Pho80p phosphorylation of yeast Pah1p phosphatidate phosphatase regulates its activity, location, abundance, and function in lipid metabolism.PMID 22334681Read ↗

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