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Article

Keratinocyte regulation of TGF‐β and connective tissue growth factor expression: A role in suppression of scar tissue formation

1 Sept 2007

Abstract excerpt

Allogeneic keratinocytes applied to large full-thickness wounds promote healing while suppressing scar tissue formation. This effect may be mediated in part by their effect on the levels of transforming growth factor-betas (TGF-betas) and connective tissue growth factor (CTGF) in the wound and subsequent modulation of fibroblast activity. We have examined the levels of TGF-beta and CTGF produced by keratinocytes...

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Identifiers

PMID: 17971021
DOI: 10.1111/j.1524-475x.2007.00281.x

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