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Article

Molecular mechanisms regulating the angiogenic phenotype in tumors: clinical impact in the future.

Anticancer research - 1 Jan 2000

Aubry Karine, Barriere Guilaine, Chable-Rabinovitch Helene, Dutour Aurelie, Paraf Francois, Monteil Jacques, Rigaud Michel

Abstract excerpt

Tumor progression depends on the angiogenic switch. In this review, we recapitulate the molecular mechanisms involved in this angiogenic switch. The rat osteosarcoma model employed would permit further studies in the sequential events leading to initial recruitment of blood vessels and could lead to development of an angiogenesis-based panel of circulating blood cells (endothelial cells, endothelial progenitor...

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PMID: 17970051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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