Article
The role of angiogenesis in tumor growth.
Seminars in cancer biology - 1 Apr 1992
Folkman J
Abstract excerpt
Experimental and clinical evidence is here assembled in support of the concept that the development of a solid tumor progresses from a prevascular phase to a vascular phase. The prevascular tumor does not induce angiogenesis, is limited in size, and rarely metastasizes. The vascularized tumor ind...
Topics
- Angiogenesis Inducing Agents
- Animals
- Gene Expression Regulation, Neoplastic
- Humans
- Mice
- Neoplasm Metastasis
- Neoplasm Transplantation
- Neoplasms
- Neoplasms, Experimental
- Neovascularization, Pathologic
- Phenotype
- Tumor Cells, Cultured