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Article

Distinct interferon signatures stratify inflammatory and dysimmune myopathies

1 Feb 2019

Abstract excerpt

Objective: The role of interferons (IFN) in the pathophysiology of primary inflammatory and dysimmune myopathies (IDM) is increasingly investigated, notably because specific neutralisation approaches may constitute promising therapeutic tracks. In present work we analysed the muscular expression of specific IFNα/β and IFNγ-stimulated genes in patients with various types of IDM. Methods: 39 patients with IDM with...

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PMID: 30886734
DOI: 10.1136/rmdopen-2018-000811

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