Article
Genome-wide association scans identify multiple confirmed susceptibility loci for Crohn's disease: lessons for study design.
Inflammatory bowel diseases - 1 Dec 2007
Tremelling Mark, Parkes Miles
Abstract excerpt
The last 12 months have seen unprecedented progress in identifying the susceptibility genes that predispose to common disease in general and Crohn's disease in particular. Success has derived from the new technique of genome-wide association scanning in large panels of cases and controls. This has itself been made possible by the sequencing of the human genome,12 development of a map of common human haplotype...
Topics
- Crohn Disease
- Genetic Predisposition to Disease
- Genome, Human
- Humans
