Article
Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.
Experimental & molecular medicine - 30 Nov 2009
Park Ji Wan, Ji Yong Ick, Choi Yoon Ho, Kang Mi Yeon, Jung Eunhyun, Cho Se Young, Cho Hee-Youn, Kang Byung Kyu, Joung Yoo Sook, Kim Duk-Hwan, Park Sang Chul, Park Joobae
Abstract excerpt
Long-lived people may have a unique genetic makeup that makes them more resistant than the general population to prevalent age-related diseases; however, not much is known about genes involved in the longevity. To identify susceptibility variants controlling longevity, we performed a high-throughput candidate gene study using 137 Koreans over 90 yr old and 213 young healthy Koreans. We evaluated 463 informative...
Topics
- Adult
- Aged
- Aged, 80 and over
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Alleles
- Asian People
- Cardiovascular Diseases
- Diabetes Mellitus
- ErbB Receptors