Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Auditory brainstem responses are impaired in EphA4 and ephrin-B2 deficient mice.

Hearing research - 1 Jan 2008

Miko Ilona J, Henkemeyer Mark, Cramer Karina S

Abstract excerpt

The Eph receptor tyrosine kinases and their membrane-anchored ligands, ephrins, are signaling proteins that act as axon guidance molecules during chick auditory brainstem development. We recently showed that Eph proteins also affect patterns of neural activation in the mammalian brainstem. However, functional deficits in the brainstems of mutant mice have not been assessed physiologically. The present study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Auditory Threshold
Share to Acoustic Stimulation
Share to Evoked Potentials, Auditory, Brain Stem

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hearing Disorders

Share to Mice, Knockout

Share to Reaction Time

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 17967521
DOI: 10.1016/j.heares.2007.09.003
PMCID: PMC3250224

Genes

ABR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Auditory brainstem responses are impaired in EphA4 and ephrin-B2 deficient mice.PMID 17967521Read ↗

On the role of ephrinA2 in auditory function.Semantic proximity Read ↗

Null mutations in EphB receptors decrease sharpness of frequency tuning in primary auditory cortex.Semantic proximity Read ↗

Graded and discontinuous EphA-ephrinB expression patterns in the developing auditory brainstem.Semantic proximity Read ↗

Ephrin-A3 is required for tonotopic map precision and auditory functions in the mouse auditory brainstem.Semantic proximity Read ↗

EphB2 guides axons at the midline and is necessary for normal vestibular function.Semantic proximity Read ↗

Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways.Semantic proximity Read ↗

Auditory evoked-potential abnormalities in a mouse model of 22q11.2 Deletion Syndrome and their interactions with hearing impairmentSemantic proximity Read ↗

Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.Semantic proximity Read ↗

Generation of an EphA4 conditional allele in mice.Semantic proximity Read ↗

Vestibular evoked myogenic potentials in normal mice and Phex mice with spontaneous endolymphatic hydrops.Semantic proximity Read ↗

Adenosine receptors regulate susceptibility to noise-induced neural injury in the mouse cochlea and hearing loss.Semantic proximity Read ↗

Hearing and vestibular deficits in the Coch(-/-) null mouse model: comparison to the Coch(G88E/G88E) mouse and to DFNA9 hearing and balance disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.