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Article

Association of TLR4 gene polymorphisms with sporadic Parkinson's disease in a Han Chinese population.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Sept 2015

Zhao Jing, Han Xun, Xue Li, Zhu Konghua, Liu Hongxin, Xie Anmu

Abstract excerpt

Parkinson's disease (PD) is considered as a multifactorial disorder involving complex interactions between genetic and environmental factors, while previous studies point to a pivotal role of neuroinflammation in the pathophysiology of PD. As a member of pattern recognition receptors, TLR4 plays an important role in the immune response and inflammatory responses. Growing evidences suggest that mutation of TLR4...

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Source

Identifiers

PMID: 25908385
DOI: 10.1007/s10072-015-2227-9

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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