Article
Toll-like receptor-9 in Spanish multiple sclerosis patients: an association with the gender.
European journal of neurology - 1 Mar 2014
Dominguez-Mozo M I, Garcia-Montojo M, López-Cavanillas M, De Las Heras V, Garcia-Martinez A, Arias-Leal A M, Casanova I, Urcelay E, Arroyo R, Alvarez-Lafuente R
Abstract excerpt
BACKGROUND AND PURPOSE: Toll-like receptor-9 (TLR9) is a potent inducer of innate immune system triggered by infection with viruses, some of them previously related to multiple sclerosis (MS). The aim of this study was to analyze the possible association of two TLR9 single nucleotide polymorphisms (SNPs; rs352162 and rs187084) with susceptibility to MS. METHODS: Two independent cohorts of MS patients and controls...
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