Article
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Jan 2009
Scherk Harald, Backens Martin, Schneider-Axmann Thomas, Kraft Susanne, Kemmer Claudia, Usher Juliana, Reith Wolfgang, Falkai Peter, Meyer Jobst, Gruber Oliver
Abstract excerpt
INTRODUCTION: Dopaminergic activity in the brain is modulated by the dopamine transporter (DAT). Several lines of evidence suggest that a variable number of tandem repeats (VNTR) polymorphism of the DAT1 gene (SLC6A3) influences its gene expression. The aim of this study was to determine whether the DAT1VNTR polymorphism alters the metabolic ratios NAA/Cho, NAA/Cr, Cho/Cr and Ins/Cr in the left dorsolateral...
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