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Article

Genetic imaging study with [Tc-99m] TRODAT-1 SPECT in adolescents with ADHD using OROS-methylphenidate.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Aug 2018

Akay Aynur Pekcanlar, Kaya Gamze Çapa, Kose Samet, Yazıcıoğlu Çiğdem Eresen, Erkuran Handan Özek, Güney Sevay Alşen, Oğuz Kaya, Keskin Duygu, Baykara Burak, Emiroğlu Neslihan İnal, Eren Mine Şencan, Kızıldağ Sefa, Ertay Türkan, Özsoylu Dua, Miral Süha, Durak Hatice, Gönül Ali Saffet, Rohde Luis Augusto

Abstract excerpt

AIM: To examine theeffects on the brain of 2-month treatment withamethylphenidate extended-release formulation (OROS-MPH) using [Tc-99m] TRODAT-1SPECT in a sample of treatment-naïve adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). In addition, to assess whether risk alleles (homozygosity for 10-repeat allele at the DAT1 gene were associated with alterations in striatal DAT availability. METHODS:...

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PMID: 29684537
DOI: 10.1016/j.pnpbp.2018.04.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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