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Article

Allelic variation in TLR4 is linked to susceptibility to Salmonella enterica serovar Typhimurium infection in chickens.

Infection and immunity - 1 Mar 2003

Leveque Gary, Forgetta Vincenzo, Morroll Shaun, Smith Adrian L, Bumstead Nat, Barrow Paul, Loredo-Osti J C, Morgan Kenneth, Malo Danielle

Abstract excerpt

Toll-like receptor 4 (TLR4) is part of a group of evolutionarily conserved pattern recognition receptors involved in the activation of the immune system in response to various pathogens and in the innate defense against infection. We describe here the cloning and characterization of the avian orthologue of mammalian TLR4. Chicken TLR4 encodes a 843-amino-acid protein that contains a leucine-rich repeat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 12595422
DOI: 10.1128/IAI.71.3.1116-1124.2003
PMCID: PMC148888

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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