Article
Low-grade gastric adenomas/dysplasias: phenotypic expression, DNA ploidy pattern, and LOH at microsatellites linked to the APC gene.
Pathology, research and practice - 1 Jan 2008
Tanaka Aiko, Takemura-Tsukashita Shizuki, Kushima Ryoji, Sugihara Hiroyuki, Fujiyama Yoshihide, Hattori Takanori
Abstract excerpt
The adenoma-adenocarcinoma sequence in the colon is generally accepted. Regarding the stomach, however, opinions about tumorigenesis are different. We analyzed the phenotypes, DNA ploidy patterns, and microsatellite regions linked to adenomatous polyposis coli (APC) gene on chromosome 5q of low-grade gastric adenomas/dysplasias, Vienna Category 3, to investigate whether these lesions have the potential to become...
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