Article
Tumor differentiation phenotype in gastric differentiated-type tumors and its relation to tumor invasion and genetic alterations.
World journal of gastroenterology - 28 Jun 2006
Yamazaki Kimiyasu, Tajima Yusuke, Makino Reiko, Nishino Nobukazu, Aoki Shigeo, Kato Masanori, Sakamoto Masaaki, Morohara Koji, Kaetsu Tsutomu, Kusano Mitsuo
Abstract excerpt
AIM: To clarify the relations between tumor differentiation phenotype and tumor invasion or genetic alterations in gastric differentiated-type tumors. METHODS: We examined the tumor differentiation phenotype, the presence of mutations in APC and p53, and the microsatellite instability (MSI) status in 48 gastric adenomas and 171 differentiated-type carcinomas. The tumor differentiation phenotype was determined by...
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