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Article

Tumor-derived death receptor 6 modulates dendritic cell development.

Cancer immunology, immunotherapy : CII - 1 Jun 2008

DeRosa David C, Ryan Paul J, Okragly Angela, Witcher Derrick R, Benschop Robert J

Abstract excerpt

Studies in murine models of cancer as well as in cancer patients have demonstrated that the immune response to cancer is often compromised. This paradigm is viewed as one of the major mechanisms of tumor escape. Many therapies focus on employing the professional antigen presenting dendritic cells (DC) as a strategy to overcome immune inhibition in cancer patients. Death receptor 6 (DR6) is an orphan member of the...

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Identifiers

PMID: 17962943
DOI: 10.1007/s00262-007-0413-1
PMCID: PMC11030700

Genes

TNF
TNFRSF21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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