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Article

IL-6 involvement in epithelial cancers.

The Journal of clinical investigation - 1 Dec 2007

Schafer Zachary T, Brugge Joan S

Abstract excerpt

In this issue of the JCI, two reports provide intriguing new information on the role of the inflammatory cytokine IL-6 in breast and lung cancer. The study by Sansone et al. implicates IL-6 in the instigation of malignant properties in breast cancer stem cells (see the related article beginning on page 3988). The study by Gao et al. identifies mutant variants of EGFR as inducers of IL-6 in lung adenocarcinomas...

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Source

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Identifiers

PMID: 18060028
DOI: 10.1172/JCI34237
PMCID: PMC2096452

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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