Article
Tourette's syndrome is not associated with interleukin-10 receptor 1 variants on chromosome 11q23.3.
Psychiatry research - 15 Jan 2008
Kindler Jochen, Schosser Alexandra, Stamenkovic Mara, Schloegelhofer Monika, Leisch Friedrich, Hornik Kurt, Aschauer Harald, Gasche Christoph
Abstract excerpt
Interleukin-10 receptor 1 (IL-10R1) single nucleotide polymorphisms, located on chromosome 11q23 - a strong candidate for linkage with Tourette's syndrome (TS) - have been investigated for association with TS. DNA of 77 patients with a DSM-IV (Diagnostic and Statistical Manual IV) diagnosis of TS and 250 healthy controls was genotyped. IL-10R1 was not associated with TS.
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