Article
Tourette syndrome is not caused by mutations in the central cannabinoid receptor (CNR1) gene.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 May 2004
Gadzicki Dorothea, Müller-Vahl Kirsten R, Heller Daniela, Ossege Sebastian, Nöthen Markus M, Hebebrand Johannes, Stuhrmann Manfred
Abstract excerpt
Tourette syndrome (TS) is a complex inherited disorder of unknown aetiology, characterized by multiple motor and vocal tics. Involvement of the central cannabinoid (CB1) system is suggested because of therapeutic effects of marijuana (Cannabis sativa L.) consumption and Delta(9)-tetrahydrocannabinol (-THC) treatment in TS patients. The central cannabinoid receptor (CNR1) gene encoding the CNR1 was considered as a...
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