Article
Characterization of connexin31.1-deficient mice reveals impaired placental development.
Developmental biology - 1 Dec 2007
Zheng-Fischhöfer Qingyi, Kibschull Mark, Schnichels Marc, Kretz Markus, Petrasch-Parwez Elisabeth, Strotmann Jörg, Reucher Harald, Lynn Bruce D, Nagy James I, Lye Stephen J, Winterhager Elke, Willecke Klaus
Abstract excerpt
The gap junction gene Connexin31.1 has been reported to be expressed predominantly in the epidermis of murine skin. To study the function of this gene, we generated mice in which the coding DNA of the Connexin31.1 gene was replaced by lacZ reporter coding DNA. Using beta-galactosidase staining, we have shown that lacZ/Connexin31.1 was expressed in the spinous and granular layers of the epidermis, in cells of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
