Article
The connexin 30.3 of zebrafish homologue of human connexin 26 may play similar role in the inner ear.
Hearing research - 1 Jul 2014
Chang-Chien Ju, Yen Yung-Chang, Chien Kuo-Hsuan, Li Shaun-Yow, Hsu Tsai-Ching, Yang Jiann-Jou
Abstract excerpt
The intercellular gap junction channels formed by connexins (CXs) are important for recycling potassium ions in the inner ear. CXs are encoded by a family of the CX gene, such as GJB2, and the mechanism leading to mutant connexin-associated diseases, including hearing loss, remains to be elucidated. In this study, using bioinformatics, we found that two zebrafish cx genes, cx27.5 and cx30.3, are likely homologous...
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