Article
Gene expression analysis from human immunodeficiency virus type 1 subtype C promoter and construction of bicistronic reporter vectors.
AIDS research and human retroviruses - 1 Oct 2007
Siddappa Nagadenahalli Byrareddy, Kashi Venkatesh Prasanna, Venkatramanan Mohanram, Balasiddaiah Anangi, Jayasuryan Narayana, Mahadevan Anita, Desai Anita, Satish Kadappa S, Shankar Susarla K, Ravi Vasanthapuram, Ranga Udaykumar
Abstract excerpt
We report the cloning and sequence analysis of the long terminal repeat (LTR) of several primary HIV-1 subtype C strains of India. Phylogenetically, all the LTRs and the paired env sequences clustered with subtype C reference strains. The LTRs demonstrated extensive polymorphism in the transcription factor binding sites (TFBS) within the enhancer and the modulator regions. We generated reporter vectors under the...
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