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Article

An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise.

Retrovirology - 19 Sept 2021

Ali Haider, Bhange Disha, Mehta Kavita, Gohil Yuvrajsinh, Prajapati Harshit Kumar, Byrareddy Siddappa N, Buch Shilpa, Ranga Udaykumar

Abstract excerpt

BACKGROUND: We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral modulatory region or enhancer, including RBEIII, LEF-1, Ap-1 and/or NF-κB. These sites are crucial for governing viral gene expression and latency. Here, we infer that one variant viral promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34538278
DOI: 10.1186/s12977-021-00572-2
PMCID: PMC8451104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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