Article
Transgenic models of skin diseases.
Archives of dermatology - 1 Nov 1993
Rothnagel J A, Greenhalgh D A, Wang X J, Sellheyer K, Bickenbach J R, Dominey A M, Roop D R
Abstract excerpt
BACKGROUND: Transgenic animals have greatly enhanced our understanding of the contribution of various structural and regulatory components to epidermal biology. The expression of mutant versions of these components in the epidermis of transgenic mice has generated animal models of specific human...
Topics
- Animals
- Animals, Newborn
- Epidermal Growth Factor
- Gene Expression
- Genes, Dominant
- Genes, fos
- Genes, ras
- Humans
- Keratins
- Mice
- Mice, Transgenic
- Models, Biological
- Mutation
- Phenotype
- Skin
- Skin Diseases
- Skin Neoplasms
- Transforming Growth Factor alpha
