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TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo

29 Mar 2022

Abstract excerpt

BACKGROUND: Dermal papilla cells (DPCs) are one type of mesenchymal cells; they play a key role on hair follicle induction. Their hair inductivity and proliferation abilities are rapidly lost during the 2-dimensional culture. Cell senescence is induced by inadequate culture conditions and telomere shortening. We previously reported that overexpression of TERT coding telomerase reverse transcriptase and BMI1...

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PMID: 35440400
DOI: 10.1016/j.jdermsci.2022.03.009

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