Article
[Association of a polymorphic marker C825T of the beta(3) subunit of G-protein with myocardial hypertrophy in patients with hypertensive disease].
Kardiologiia - 1 Jan 2003
Shliakhto E V, Shwarts E I, Sokolova L A, Nefedova Iu B, Zhukova A V, Vinnik T A, Tolstova I A, Rudomanov O G, Konradi A O
Abstract excerpt
AIM: To elucidate association of a polymorphic marker C825T of the beta(3)-subunit of G-protein with myocardial hypertrophy in hypertension. MATERIAL AND METHODS: Alleles of polymorphic marker C825T of the CNB3 gene were identified by polymerase chain reaction with subsequent cleavage of the product by BseDI restrictase in 135 patients with hypertensive disease (essential hypertension). Left ventricular mass was...
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