Article
Genetic determinants of plasma lipoproteins.
Nature clinical practice. Cardiovascular medicine - 1 Nov 2007
Pollex Rebecca L, Hegele Robert A
Abstract excerpt
The search for common genetic determinants of plasma lipoproteins began in the early 1980s. Despite some exceptions, these efforts have not yet yielded a set of biological markers that can be used in clinical practice. By contrast, successes in defining the molecular basis of rare single-gene disorders, such as familial hypoalphalipoproteinemia, have shown the value of experimental designs that focus on genomic...
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