Pharmacogenomics Variability of Lipid-Lowering Therapies in Familial Hypercholesterolemia

Abstract excerpt

The exponential expansion of genomic data coupled with the lack of appropriate clinical categorization of the variants is posing a major challenge to conventional medications for many common and rare diseases. To narrow this gap and achieve the goals of personalized medicine, a collaborative effort should be made to characterize the genomic variants functionally and clinically with a massive global genomic...

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