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Article

A novel noncoding RNA rescues mutant SOD1-mediated cell death.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2008

Chang Yueming, Stockinger Michael P, Tashiro Hirofumi, Lin Chien-liang Glenn

Abstract excerpt

Transgenic mice expressing mutant Cu2+/Zn2+ superoxide dismutase SOD1(G93A) develop similar clinical and pathological phenotypes to amyotrophic lateral sclerosis (ALS) patients. Here, we utilize representational difference analysis to identify the transcripts that are up-regulated in the presymptomatic stage of SOD1(G93A) mice. Unexpectedly, three predominant clones were 18S or 28S ribosomal RNA (rRNA) segments....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17957031
DOI: 10.1096/fj.07-9532com

Genes

SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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