Article
Noise reduction from genotyping microarrays using probe level information.
In silico biology - 1 Jan 2006
Komura Daisuke, Nishimura Kunihiro, Ishikawa Shumpei, Panda Binaya, Huang Jing, Nakamura Hiroshi, Ihara Sigeo, Hirose Michitaka, Jones Keith W, Aburatani Hiroyuki
Abstract excerpt
Genomic copy number change is one of the important phenomenon observed in cancer and other genetic disorders. Recently oligonucleotide microarrays have been used to analyze changes in the copy number. Although high density microarrays provide genome wide useful data on copy number, they are often associated with substantial amount of experimental noise that could affect the performance of the analyses. We used...
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