Article
Comparative evaluation of three JAK2V617F mutation detection methods.
American journal of clinical pathology - 1 Nov 2007
Frantz Christine, Sekora Donna M, Henley Donald C, Huang Chih-Kang, Pan Qiulu, Quigley Neil B, Gorman Eric, Hubbard Roger A, Mirza Imran
Abstract excerpt
The correlation of JAK2V617F with a proportion of chronic myeloproliferative disorders has generated numerous studies focused on the development of molecular-based assays for JAK2V617F detection. The current parallel study comparatively evaluated 3 JAK2V617F molecular detection methods. Genomic DNA from blood or bone marrow was assayed by 3 laboratories using allele-specific polymerase chain reaction (AS-PCR) or...
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