Article
Status of donor-recipient HLA class I ligands and not the KIR genotype is predictive for the outcome of unrelated hematopoietic stem cell transplantation in beta-thalassemia patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Nov 2007
La Nasa Giorgio, Littera Roberto, Locatelli Franco, Giardini Claudio, Ventrella Arianna, Mulargia Marina, Vacca Adriana, Orrù Nicola, Orrù Sandro, Piras Eugenia, Giustolisi Giada, Lisini Daniela, Nesci Sonia, Caocci Giovanni, Carcassi Carlo
Abstract excerpt
Several studies have investigated the role played by killer immunoglobulin-like receptors (KIRs) and their ligands on the outcome of hematopoietic stem cell transplantation (HSCT) in patients affected by oncohematologic diseases. However, the interpretation of the results of these studies is considerably hampered by the heterogeneity of the diseases, disease status at transplantation, and the different protocols...
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