Article
KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.
Bone marrow transplantation - 1 Jul 2009
Ludajic K, Balavarca Y, Bickeböller H, Rosenmayr A, Fae I, Fischer G F, Kouba M, Pohlreich D, Kalhs P, Greinix H T
Abstract excerpt
Interactions of polymorphic killer Ig-like receptor (KIR) receptors with KIR ligands have been shown to modify the outcome of hematopoietic SCT (HSCT). The association of these genetic factors with different transplantation endpoints, however, varies substantially, depending on clinical and study setup variables. We aimed to assess whether KIR ligands, KIR genes and KIR haplotypes are associated with HSCT outcome...
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