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Article

Nuclear structure and the three‐dimensional organization of DNA

1 Dec 1991

Abstract excerpt

The organization of DNA within the nucleus has been demonstrated to be both cell and tissue specific and is arranged in a non-random fashion in both sperm and somatic cells. Nuclear structure has a pivotal role in this three-dimensional organization of DNA and RNA and contributes as well to forming fixed organizing sites for nuclear functions, such as DNA replication, transcription, and RNA processing. In sperm,...

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PMID: 1795013
DOI: 10.1002/jcb.240470402

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