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Non-genetic contributions of the sperm nucleus to embryonic development

18 Oct 2010

Abstract excerpt

Recent data from several laboratories have provided evidence that the newly fertilized oocyte inherits epigenetic signals from the sperm chromatin that are required for proper embryonic development. For the purposes of this review, the term epigenetic is used to describe all types of molecular information that are transmitted from the sperm cell to the embryo. There are at least six different forms of epigenetic...

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PMID: 20953203
DOI: 10.1038/aja.2010.75

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