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Article

The sperm nuclear matrix is required for paternal DNA replication

5 Apr 2007

Abstract excerpt

The mammalian sperm nucleus provides an excellent model for studying the relationship between the formation of nuclear structure and the initiation of DNA replication. We previously demonstrated that mammalian sperm nuclei contain a nuclear matrix that organizes the DNA into loop domains in a manner similar to that of somatic cells. In this study, we tested the minimal components of the sperm nucleus that are...

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PMID: 17415751
DOI: 10.1002/jcb.21321

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