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Article

A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2008

Kissling Christian, Retz Wolfgang, Wiemann Stefan, Coogan Andrew N, Clement R Marc, Hünnerkopf Regina, Conner Alex C, Freitag Christine M, Rösler Michael, Thome Johannes

Abstract excerpt

Attention-deficit hyperactivity disorder (ADHD) is frequently found in childhood and persists in about 50% of cases into adulthood. Several studies demonstrate a relationship between ADHD, circadian rhythmicity and sleeping disturbances in unmedicated ADHD patients. Since ADHD is a very complex disease with a high genetic load involving multiple genes of moderate effect, we hypothesized a link between adult ADHD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17948273
DOI: 10.1002/ajmg.b.30602

Genes

CLOCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder.PMID 17948273Read ↗

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The potential role of clock genes in children attention-deficit/hyperactivity disorder.Semantic proximity Read ↗

Human CRY1 variants associate with attention deficit/hyperactivity disorder.Semantic proximity Read ↗

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