Article
The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects.
Journal of sleep research - 1 Dec 2002
Robilliard Donna L, Archer Simon N, Arendt Josephine, Lockley Steven W, Hack Lisa M, English Judie, Leger Damien, Smits Marcel G, Williams Adrian, Skene Debra J, Von Schantz Malcolm
Abstract excerpt
Mutations in clock genes are associated with abnormal circadian parameters, including sleep. An association has been reported previously between a polymorphism (3111C), situated in the 3'-untranslated region (3'-UTR) of the circadian gene Clock and evening preference. In the present study, this p...
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